Reportedly, kids who obtained radiotherapy for the brain tumor can experience cognitive problems afterward in life. In the new study on mice, researchers from Karolinska Institutet showed that the drug lithium can aid in reversing the harm induced long after it has happened. The study findings were published in the journal Molecular Psychiatry and the scientists are now intending to examine the treatment in clinical experiments. These days, almost 4 out of 5 kids having a brain tumor sustain. As noted in the adult Swedish population, about 1 in 600 people were treated for cancer in childhood and about one-third of which were diagnosed as brain tumors. Several of them survived with damage lead by the radiotherapy and deficiencies in learning and memory.
Researchers in Sweden now demonstrate that the learning capability and memory capacity of mice advanced if lithium therapy was given following the irradiation of the brain. They reported mice—those irradiated early in life and then administered with lithium from teenage years until young adulthood—performed well as mice that were not administered with radiation. Researchers also observed an augment in the development of new neurons in a region that is significant to the memory—the hippocampus—in the period wherein they received lithium, but their development into full nerve cells only occurred once the lithium therapy was discontinued.
Recently, Karolinska Institutet was in news for its study that stated that new genetic analysis develops the identification of intellectual disability. Apparently, entire-genome sequencing can be utilized to identify intellectual disability more precisely compared to other methods of genetic analysis, scientists reported. The study was published in the journal Genome Medicine. Whole-genome sequencing utilizing analytical tools advanced by the investigators will now be established for first-line clinical analysis at Karolinska University Laboratory, Sweden.
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